AlphaFold has revealed millions of intricate 3D protein structures, and is helping scientists understand how life’s molecules interact.

What is AlphaFold?

Proteins underpin every biological process, in every living thing.

Made from long chains of amino acids, each has a unique complex 3D structure. But figuring out just one of these can take several years, and hundreds of thousands of dollars. In 2020, AlphaFold solved this problem, with the ability to predict protein structures in minutes, to a remarkable degree of accuracy.

That’s helping researchers understand what individual proteins do and how they interact with other molecules. So valuable time and resources can be redirected into advancing research that could help solve society’s biggest medical and environmental challenges.

What took us months and years to do, AlphaFold was able to do in a weekend.

Professor John McGeehan
Former Director for the Centre for Enzyme Innovation (CEI)

Over 2 million researchers in over 190 countries are using the AlphaFold Protein Structure Database to inform their research.


AlphaFold’s impact

AlphaFold has already made a significant impact. We hope it will eventually help to transform our understanding of the biological world.

So far, AlphaFold has predicted over 200 million protein structures – nearly all catalogued proteins known to science. The AlphaFold Protein Structure Database makes this data freely available. So far, it has over two million users in 190 countries. That means it has already potentially saved millions of dollars and hundreds of millions of years in research time.

Meanwhile, AlphaFold Server predicts how proteins will interact with a broad spectrum of biomolecules, accelerating new research.

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Up to 1 billion

Research years saved by AlphaFold database structures.

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Over 600,000

Users in low and middle income countries.

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21%

Of papers citing AlphaFold are related to the study of disease.


Accelerating breakthroughs

Scientists are using AlphaFold to accelerate research in nearly every field of biology.

AlphaFold has allowed us to take our project to the next level, from a fundamental science stage to the preclinical and clinical development stage.

Professor Matthew Higgins
Biochemist
AlphaFold Server

Powered by AlphaFold 3 — AlphaFold Server predicts how proteins will interact with other molecules throughout cells.


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A powerful suite of tools, helping the scientific community advance research.